About us

People | Find us | Publications | Advisory Committee

People

Iban Ubarretxena

Scientific Directorivan.ubarrechena@ehu.eus

David Gil-Carton

Technical Directordavid.gil@ehu.eus

Kristina Barragán Sanz

Cryo-EM specialistkristina.barragan@ehu.eus

Jorge P. López-Alonso

Image processing specialistjorgepedro.lopez@ehu.eus

Saioa Suárez Bilbao

Cryo-FIB-SEM specialistsaioa.suarez@ehu.eus

Andrés Jiménez

IT specialistandres.jimenez@ehu.eus

Find us

BREM is located at Instituto Biofisika in the Scientific Park of the UPV/EHU in the metropolitan area of Bilbao

Address:

Basque Resource for Electron Microscopy (BREM)

Fundación Biofísica Bizkaia and

Instituto Biofisika (UPV/EHU, CSIC)

UPV/EHU Scientific Park

Barrio Sarriena s/n | 48940 - Leioa - Bizkaia (Spain)

email: brem@ehu.eus

𝕏: brforem

Publications

2024

A resurrected ancestor of Cas12a expands target access and substrate recognition for nucleic acid editing and detection

Jabalera Y, Tascón I, Samperio S, López-Alonso JP, Gonzalez-Lopez M, Aransay AM, Abascal-Palacios G, Beisel CL, Ubarretxena-Belandia I & Perez-Jimenez R

Nat Biotechnol (2024) 1-10

https://doi.org/10.1038/s41587-024-02461-3

Structural basis for regulated expression of a CBASS- CRISPR-Cas defense island by a membrane anti-σ factor and its ECF σ partner

Bernal-Bernal D, Pantoja-Uceda D, López-Alonso JP, Tascón I, López-Rojo A, Ochoa-Lizarralde B, López-Ruiz JA, Galbis-Martínez M, Elías-Arnanz M, Ubarretxena-Belandia I & Padmanabhan S

Science Adv (2024) 10, eadp 1053

https://doi.org/10.1126/sciadv.adp1053

Molecular basis for transposase activation by a dedicated AAA+ ATPase

Gándara A, Spínola-Amilibia M, Araújo-Bazán L, Núñez-Ramírez R, Berger JM & Arias-Palomo E

Nature (2024) 630, 1003-1011

https://doi.org/10.1038/s41586-024-07550-6

Membrane fission via transmembrane contact

Spencer RKW, Santos-Pérez I, Rodríguez-Renovales I, Martinez Galvez JM, Shnyrova AV & Müller M

Nat Commun (2024) 15, 2793

https://doi.org/10.1038/s41467-024-47122-w

Mechanism of allosteric inhibition of RUVBL1-RUVBL2 ATPase by the small molecule CB-6644

García-Martín C, López-Perrote A, Boskovic J & Llorca O

Cell Rep Phys Sci (2024) 5, 101982

https://doi.org/10.1016/j.xcrp.2024.101982

Transition of human γ-tubulin ring complex into a closed conformation during microtubule nucleation

Brito C, Serna M, Guerra P, Llorca O & Surrey T

Science (2024) 383, 870-876

https://doi.org/10.1126/science.adk6160

2023

Structural and functional insights into the delivery of a bacterial Rhs pore-forming toxin to the membrane.

Magaña A, Tascón I, Altuna-Alvarez J, Queralt-Martin M, Colautti J, Velázquez C, Zabala M, Rojas-Palomino J, Cárdenas M, Alcaraz A, Whitney JC, Ubarretxena-Belandia I & Albesa-Jové D

Nat Commun (2023) 14, 7808

https://doi.org/10.1038/s41467-023-43585-5